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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYST2
All Species:
26.36
Human Site:
S158
Identified Species:
41.43
UniProt:
O95251
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95251
NP_008998.1
611
70642
S158
E
S
I
A
K
D
M
S
L
K
D
S
G
S
D
Chimpanzee
Pan troglodytes
XP_511869
806
91579
S353
E
S
I
A
K
D
M
S
L
K
D
S
G
S
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548192
555
64081
F119
H
R
P
K
R
R
R
F
H
E
S
Y
N
F
N
Cat
Felis silvestris
Mouse
Mus musculus
Q5SVQ0
613
70623
S160
E
S
I
A
K
D
M
S
L
K
D
S
G
S
D
Rat
Rattus norvegicus
Q810T5
612
70496
S159
E
S
I
A
K
D
M
S
L
K
D
S
G
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026512
611
70527
S158
E
S
I
A
K
D
M
S
M
K
D
S
G
S
D
Frog
Xenopus laevis
NP_001079995
617
71123
S158
E
S
V
A
K
D
M
S
L
K
D
S
E
S
D
Zebra Danio
Brachydanio rerio
NP_997800
568
65560
R132
D
P
S
H
R
P
K
R
R
R
F
H
E
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960X4
541
61216
S105
T
T
P
Q
R
H
H
S
L
A
G
S
V
S
R
Honey Bee
Apis mellifera
XP_392324
916
101344
G450
N
R
I
P
Q
N
S
G
T
S
N
A
T
T
G
Nematode Worm
Caenorhab. elegans
Q9TYU5
458
53125
T22
G
I
S
K
K
I
P
T
D
P
R
Q
Y
E
K
Sea Urchin
Strong. purpuratus
XP_782361
504
58083
V68
P
M
K
T
G
K
G
V
D
R
K
T
S
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXD7
445
51348
T9
G
S
S
A
N
T
E
T
N
G
N
A
P
P
P
Baker's Yeast
Sacchar. cerevisiae
Q08649
445
52594
P9
S
H
D
G
K
E
E
P
G
I
A
K
K
I
N
Red Bread Mold
Neurospora crassa
Q7S9B6
506
58788
E70
N
F
N
K
R
L
D
E
W
V
P
A
A
R
I
Conservation
Percent
Protein Identity:
100
75.8
N.A.
89.3
N.A.
99
99
N.A.
N.A.
97.8
93.1
76.4
N.A.
33.7
34
30.9
39.2
Protein Similarity:
100
75.8
N.A.
89.5
N.A.
99
99
N.A.
N.A.
98.5
95.9
83.4
N.A.
49.5
48.1
48.6
53.8
P-Site Identity:
100
100
N.A.
0
N.A.
100
100
N.A.
N.A.
93.3
86.6
6.6
N.A.
26.6
6.6
6.6
0
P-Site Similarity:
100
100
N.A.
20
N.A.
100
100
N.A.
N.A.
100
93.3
26.6
N.A.
40
40
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
31.9
31.2
Protein Similarity:
N.A.
N.A.
N.A.
50.4
47.6
47.4
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
47
0
0
0
0
0
7
7
20
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
0
0
40
7
0
14
0
40
0
0
7
40
% D
% Glu:
40
0
0
0
0
7
14
7
0
7
0
0
14
7
0
% E
% Phe:
0
7
0
0
0
0
0
7
0
0
7
0
0
7
0
% F
% Gly:
14
0
0
7
7
0
7
7
7
7
7
0
34
0
7
% G
% His:
7
7
0
7
0
7
7
0
7
0
0
7
0
0
0
% H
% Ile:
0
7
40
0
0
7
0
0
0
7
0
0
0
7
7
% I
% Lys:
0
0
7
20
54
7
7
0
0
40
7
7
7
0
7
% K
% Leu:
0
0
0
0
0
7
0
0
40
0
0
0
0
0
0
% L
% Met:
0
7
0
0
0
0
40
0
7
0
0
0
0
0
0
% M
% Asn:
14
0
7
0
7
7
0
0
7
0
14
0
7
0
14
% N
% Pro:
7
7
14
7
0
7
7
7
0
7
7
0
7
7
7
% P
% Gln:
0
0
0
7
7
0
0
0
0
0
0
7
0
0
0
% Q
% Arg:
0
14
0
0
27
7
7
7
7
14
7
0
0
7
7
% R
% Ser:
7
47
20
0
0
0
7
47
0
7
7
47
7
54
7
% S
% Thr:
7
7
0
7
0
7
0
14
7
0
0
7
7
7
0
% T
% Val:
0
0
7
0
0
0
0
7
0
7
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _